Could using the zona pellucida bound sperm for intracytoplasmic sperm injection (ICSI) enhance the outcome of ICSI?

Could using the zona pellucida bound sperm for intracytoplasmic sperm injection (ICSI) enhance the outcome of ICSI?

I n the recent literature, several interesting articles have been published using the zona pellucdia (ZP)-bound sperm for intracytoplasmic sperm injection (ICSI) to enhance embryo quality, implantation and clinical pregnancy rates. The three studies were performed independently in different ART clinics. In the test group, patients’ sibling immature (either germinal vesicle (GV) or metaphase I) ...

Intracytoplasmic sperm injection (ICSI).

Intracytoplasmic sperm injection (ICSI)

IVF has become a well-established treatment for certain types of infertility, including long-standing infertility due to tubal disease, endometriosis, unexplained infertility or infertility involving a male factor. Soon it became clear that certain couples with severe male-factor infertility could not be helped by conventional IVF. Extremely low sperm counts, impaired motility and/or abnormal m...

Piezo-actuated Mouse ICSI (Intracytoplasmic sperm injection)

Intracytoplasmic sperm injection (ICSI) is not only used in human assisted reproduction (ART), but it is also widely employed for veterinary in vitro fertilization during rare species preservation, germ-line rescue of transgenic animals or for any veterinary assisted conception. Piezo-assisted ICSI, which was first described in 1995 [1], can be employed for assisted conception in animals in whi...

Male infertility and intracytoplasmic sperm injection (ICSI).

Micro-assisted fertilization in the form of intracytoplasmic sperm injection (ICSI) has truly revolutionised the treatment options for couples with impaired semen quality, and those with both obstructive and non-obstructive azoospermia. In general, the major issues which relate to the success of ICSI are those related to the success of conventional IVF, and the high multiple pregnancy rate rema...